@trevorflowers np.
I just dabbled with some of those ideas and have seen several setups that utilize #Watercooling on the #RasberryPi to save space...
Also it'll make certainly sense to go with a cooling system similar to the "Trashcan" #MacPro based off the exterior of a classic #Cray...
@trevorflowers for example #alphacool has the distributor block [shop.alphacool.com] and the tiny waterblock [shop.alphacool.com] I'd intended to use...
They even have a chonky 120mm radiator [shop.alphacool.com] with 4 ports so you can easily [partially!] fill such a passive phase changing loop from the top...
Just please don't use water for a phase-changing cooling [en.wikipedia.org] system because even if you keep it sub-ambient, the vapour expansion to 1700x volume will either make it not work at all or potentially explode the hoses in your face like some high-pressure hydraulics line...
But for the use-case of a design-first case, a phase-changing termosiphon cooling [en.wikipedia.org] is propably the most effective unless you'd choose to custom-build a giant-ass heatsink with heatpipes like the trashcan Mac Pro [www.youtube.com], tho that'll likely be way too expensive to even prototype!